Hydrocortisone Cream
Topical glucocorticoid
Also sold as Cortizone
Effect timeline
Approximate single-dose timeline. Onset shows when effects are felt; Tmax shows when blood levels peak.
Notes
OTC up to 1%.
Hydrocortisone Cream is a topical glucocorticoid given by the topical route. It's typically used in the corticosteroid category.
After one topical dose you'd typically start noticing the effect in 1 hr – 4 hr. The drug reaches its highest blood level in about 4 hr – 8 hr, and a single dose usually keeps working for around 8 hr – 12 hr.
Apply to clean, dry skin and wash hands after.
Don't combine with other products in the same drug class without checking with a pharmacist. Stop and seek medical advice if you have an unexpected reaction, severe side effect, or symptoms that don't improve.
All timings are approximate population ranges for a typical adult dose. Individual response varies with age, genetics, formulation, food, and other medications.
Typical dosing
Source: OpenFDA drug label · adult dosing unless noted
Doses vary by age, weight, kidney/liver function, and indication. Don't change your dose without talking to your prescriber.
Verify on the exact label used:DailyMed search·OpenFDA record
Side effects & warnings
Source: OpenFDA drug label
Verify on the exact label used:DailyMed search·OpenFDA record
Educational information only — not medical advice. Times vary by person, dose, and formulation. Always consult a doctor or pharmacist for personal guidance.