Capsaicin Cream
TRPV1 agonist
Also sold as Zostrix
Cumulative therapeutic effect
Sustained pain relief develops over 2–4 weeks of regular use.
Effect timeline
Approximate single-dose timeline. Onset shows when effects are felt; Tmax shows when blood levels peak.
Notes
Burning sensation at first; apply 3–4× daily.
Capsaicin Cream is a trpv1 agonist given by the topical route. It's typically used in the pain relief category.
After one topical dose you'd typically start noticing the effect in 5 min – 30 min. The drug reaches its highest blood level in about 1 hr – 2 hr, and a single dose usually keeps working for around 4 hr – 6 hr.
Take consistently — the full benefit builds over time, not from a single dose. Apply to clean, dry skin and wash hands after. Short-acting — don't re-dose sooner than the label allows.
Don't combine with other products in the same drug class without checking with a pharmacist. Stop and seek medical advice if you have an unexpected reaction, severe side effect, or symptoms that don't improve.
All timings are approximate population ranges for a typical adult dose. Individual response varies with age, genetics, formulation, food, and other medications.
Typical dosing
Source: OpenFDA drug label · adult dosing unless noted
Doses vary by age, weight, kidney/liver function, and indication. Don't change your dose without talking to your prescriber.
Verify on the exact label used:DailyMed search·OpenFDA record
Side effects & warnings
Source: OpenFDA drug label
Verify on the exact label used:DailyMed search·OpenFDA record
Educational information only — not medical advice. Times vary by person, dose, and formulation. Always consult a doctor or pharmacist for personal guidance.